Predictive factors of the interruption of exclusive breastfeeding in premature infants: a prospective cohort

ABSTRACT Objective: to evaluate the incidence of exclusive breastfeeding and the risk factors associated to its interruption in premature infants after hospital discharge. Method: this is a prospective cohort with 113 premature infants in a neonatal unit, whom were followed-up from 7 to 15 days after hospital discharge. The outcome was the interruption of exclusive breastfeeding. Maternal and neonatal exposure variables were evaluated by a regression model and described by the confidence interval (95%) and risk ratio. Results: exclusive breastfeeding rate was 81.4% at discharge and 66.4% at 7 to 15 days after discharge. Double gestation, time of mechanical ventilation and birth weight were associated with higher risks of interruption of exclusive breastfeeding after discharge. Conclusion: there is a need for the implementation of actions that promote the early onset and maintenance of exclusive breastfeeding of premature infants.

摘要 目的：评估早产儿出院后纯母乳喂养的发生率及其中断的相关危险因素。方法：本研究为前瞻性队列研究，纳入新生儿病房的113名早产儿，于其出院后7~15天开展随访。本研究的结局指标为纯母乳喂养中断。采用回归模型对母婴暴露变量进行分析，并以95%置信区间与风险比进行结果描述。结果：出院时纯母乳喂养率为81.4%，出院后7~15天时该比例降至66.4%。双胎妊娠、机械通气时长及出生体重与出院后纯母乳喂养中断的更高风险相关。结论：需实施相关措施以促进早产儿纯母乳喂养的早期启动与维持。