PV-INPATIENT

Reporting adverse drug reactions (ADRs) by patients may contribute to the improvement of drug safety. Thence, we evaluated Turkish inpatients’ knowledge, attitude, and practice regarding pharmacovigilance in a university hospital in Turkey. An observational, cross-sectional study was performed by a face-to-face questionnaire in 260 inpatients. The mean score of knowledge level (1.38 ± 0.12) was far below that of maximum score (15 points). Although 245 of 260 inpatients (94.62%) were aware of side effects, only 18 of them (6.92%) had heard about the pharmacovigilance term and the Turkish Pharmacovigilance Center. Ten of 18 subjects (55.56%) knew that they could directly report ADRs via the reporting form. Forty-two percent of inpatients had experienced ADRs in the past, 69.16% of them preferred to consult the doctor of concern, stopping the drug being the most selected intervention (60.75%). Solely 11.11% of those who were aware of Turkish Pharmacovigilance Center (n=18) reported ADRs to the center. The knowledge, attitude, and practice of Turkish inpatients about pharmacovigilance is insufficient and should be stimulated via several ways to increase the rate of spontaneous reporting of ADRs and to ensure more sensitive attitude.

患者报告药品不良反应（ADRs）或有助于提升用药安全性。为此，我们对土耳其某大学医院的住院患者开展了药物警戒（pharmacovigilance）认知、态度及实践情况的评估。本研究为观察性横断面研究，通过面对面问卷形式调查了260名住院患者。结果显示，患者认知水平平均得分为1.38±0.12分，远低于满分15分。在260名患者中，尽管有245人（94.62%）知晓药物副作用，但仅18人（6.92%）听说过药物警戒术语及土耳其药物警戒中心；这18人中，仅10人（55.56%）了解可通过报告表直接上报ADRs。此外，42%的患者曾经历过ADRs，其中69.16%的患者倾向于咨询主管医生，而停药是最常被选择的干预措施（占比60.75%）。在知晓土耳其药物警戒中心的18人中，仅11.11%曾向该中心上报过ADRs。综上，土耳其住院患者对药物警戒的认知、态度及实践均存在不足，需通过多种途径加以改善，以提高ADRs自发上报率并培养更敏锐的药物安全意识。