Effect of rivastigmine treatment on macroscopic parameters of acute colitis in mice treated with DSS.

DDS = dextran sulphate solution. PBS phosphate buffered saline. Riv 0.5 or 1 = mice treated with rivastigmine (0.5 or 1 mg/kg) once daily; Riv 1+ Scop 1 = mice treated with rivastigmine (1 mg/kg) once daily and scopolamine (1 mg/kg) bid; DAI = disease activity index. Significantly different from water+PBS ** p<0.01; significantly different from DSS+PBS,
‡p<0.05.
‡‡p<0.01; significantly different from DSS+Riv 0.5 mg,
#p<0.05;
##p<0.01; significantly different from DSS+Riv 1 mg/kg,
§p<0.05;
§§p<0.01.

DDS = 葡聚糖硫酸钠溶液（dextran sulphate solution）。PBS = 磷酸盐缓冲液（phosphate buffered saline）。Riv 0.5或1：指经每日单次给予利斯的明（rivastigmine，0.5或1 mg/kg）处理的小鼠；Riv 1+ Scop 1：指经每日单次给予利斯的明（1 mg/kg）且每日两次给予东莨菪碱（scopolamine，1 mg/kg）处理的小鼠；DAI = 疾病活动指数（disease activity index）。与水+PBS组相比，**p<0.01**；与DSS+PBS组相比，
‡p<0.05。
‡‡p<0.01；与DSS+Riv 0.5 mg/kg组相比，
#p<0.05；
##p<0.01；与DSS+Riv 1 mg/kg组相比，
§p<0.05；
§§p<0.01。