Additional file 2 of IRF4 and STAT3 activities are associated with the imbalanced differentiation of T-cells in responses to inhalable particulate matters

Additional file 2: Sheet data S1. Gene list of the 18 co-expressed gene modules identified from the PBMC profiling study. Sheet data S2. KEGG pathways and GO biological processes significantly enriched in the co-expressed gene modules. Sheet data S3. Enrichment of the target genes of known transcription factors in the four modules strongly correlated with PM exposure. Sheet data S4. Enrichment of the binding motifs of known transcription factors in the poised cis-regulatory regions of the genes of the four modules strongly correlated with PM exposure.

补充文件2：
工作表数据S1：从外周血单个核细胞（PBMC, Peripheral Blood Mononuclear Cell）表达谱分析研究中鉴定得到的18个共表达基因模块的基因列表。
工作表数据S2：共表达基因模块中显著富集的京都基因与基因组百科全书（KEGG, Kyoto Encyclopedia of Genes and Genomes）通路及基因本体（GO, Gene Ontology）生物过程。
工作表数据S3：与颗粒物（PM, Particulate Matter）暴露显著相关的4个模块内，已知转录因子靶基因的富集情况。
工作表数据S4：与颗粒物暴露显著相关的4个模块所对应基因的预激活顺式调控区域中，已知转录因子结合基序的富集情况。