Single-cell ATAC-seq of human cerebral organoids. Single-cell ATAC-seq of human cerebral organoids

Single cell ATAC-seq (scATAC-seq) was performed at various stages of differentiation of human pluripotent stem cells to 4 month old cerebral organoids. scATAC-seq was performed on the following days of differentiation: day 0 (pluripotent stem cell), day 4 (embryoid body), day 10 (neuroectoderm), day 15 (neuroepithelium), day 30 (1 month old cerebral organoid), day 60 (2 months old cerebral organoid), and day 120 (4 months old cerebral organoid).

本数据集针对人类多能干细胞向4月龄大脑类器官分化的多个阶段，开展了单细胞ATAC-seq（scATAC-seq）实验。本次实验覆盖的分化时间点包括：第0天（多能干细胞阶段）、第4天（拟胚体阶段）、第10天（神经外胚层阶段）、第15天（神经上皮阶段）、第30天（1月龄大脑类器官）、第60天（2月龄大脑类器官）以及第120天（4月龄大脑类器官）。