Additional file 1: of A combined epigenome- and transcriptome-wide association study of the oral masticatory mucosa assigns CYP1B1 a central role for epithelial health in smokers

CpGs from the literature associated with SPY in our data. Results are shown for the ANCOVA with SPY for all CpGs with q < 0.15 in our EWAS that map to genes harbouring a significant CpG in an EWAS on buccal swabs [22] or were reported as replicated in at least two independent EWAS on blood [32]. (XLSX 47 kb)

本数据中源自文献且与SPY相关的CpG位点（CpG）。针对本研究表观全基因组关联研究（Epigenome-Wide Association Study, EWAS）中q值小于0.15的全部CpG位点，本文展示了纳入SPY因素的协方差分析（Analysis of Covariance, ANCOVA）结果；上述CpG位点需满足以下任一条件：要么定位到在颊拭子表观全基因组关联研究[22]中存在显著CpG位点的基因，要么在至少两项独立的血液表观全基因组关联研究[32]中被报道得到重复验证。（XLSX 47 kb）