Schultz, T.W. Structure-Toxicity Relationships for Benzenes Evaluated with Tetrahymena pyriformis. Chem. Res. Toxicol. 1999, 12, 12, 1262–1267.
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Toxicity data for 200 substituted benzenes tested in the two-day Tetrahymena pyriformis population growth impairment assay representing the neutral narcosis, polar narcosis, respiratory uncoupling, and weak and strong electrophilic mechanisms of toxic action were evaluated. A quantitative structure-toxicity model correlating toxic potency [log(IGC(50)(-)(1))] ...
本研究针对200种取代苯（substituted benzenes）的毒性数据开展评估，上述受试样本均通过为期两天的梨形四膜虫（Tetrahymena pyriformis）种群生长抑制试验完成检测，且分别对应中性麻醉、极性麻醉、呼吸解偶联以及强弱亲电毒性作用四类作用机制。本研究构建了关联毒性效能[log(IGC₅₀⁻¹)]的定量结构-毒性模型……
提供机构：
Villu Ruusmann
创建时间：
2012-05-23
