Experimental data exploring the effects of intranasal oxytocin on young adult social preference and attachment to romantic partners, parents, friends, and strangers.

Experimental studies exploring the effects of intranasal oxytocin are typically underpowered due to small samples. Open access to experimental data and procedures and the use of previously employed measures is critical to building more robust and replicable findings, especially in less studied areas of oxytocin research. In this paper, data is provided from a double-blind placebo-controlled crossover study exploring the effects of intranasal oxytocin (IN-OT: 24 IU) on social preference to romantic partners, parents, peers, and strangers. Young adults (N=44; 91% female) in committed dating relationships completed three phases of data collection including a screening survey followed by two laboratory visits. In addition to romantic partner-, and stranger attraction ratings, the data is the first to provide comparisons between attachment and social preference ratings to parents, close friends, and romantic partners under placebo and IN-OT conditions. The data also include differences by situational and life history factors known to moderate oxytocin effects. The detailed protocol, and dataflow can be accessed to verify the analysis and findings or to conduct a replication study. The standardized experimental design and common IN-OT protocol add to the capacity for a meta-analysis exploring oxytocin effects on partner preference, and may also be directly ported to existing or future studies with related questions to increase sample size and power.

探索鼻内催产素作用的实验研究通常因样本量偏小而统计效力不足。开放获取实验数据与实验流程、复用既往采用的测量工具，对于获得更稳健、可重复的研究结果至关重要，在催产素研究中尚未得到充分探索的领域尤为如此。本数据集源自一项双盲安慰剂对照交叉研究，该研究探讨了鼻内催产素（intranasal oxytocin，IN-OT：24国际单位）对浪漫伴侣、父母、同辈及陌生人的社交偏好的影响。本研究纳入44名处于稳定恋爱关系的年轻成年人（其中91%为女性），他们完成了三阶段的数据收集流程：首先完成一项筛查问卷，随后进行两次实验室访视。除浪漫伴侣与陌生人的吸引力评分外，本数据集首次提供了安慰剂组与IN-OT组中，父母、密友及浪漫伴侣的依恋评分与社交偏好评分的对比数据。数据集还涵盖了已知可调节催产素作用的情境因素与生活史因素所带来的组间差异。研究者可获取详细的实验方案与数据流信息，以验证本研究的分析与结果，或开展重复研究。本研究采用的标准化实验设计与通用IN-OT方案，可为探讨催产素对伴侣偏好影响的元分析提供数据支持，同时也可直接应用于现有或未来的相关研究，以提升样本量与统计效力。