Effects of a seven-week running intervention with moderate intensity on the volume of the hippocampus and depressive symptoms in young men from the general population.

STUDY DESCRIPTION: A within-subjects-design involving a two-week baseline period before the running intervention, and two subsequent intervention cycles was applied. At four time points of assessment (t1: start of the study; t2: end of baseline period/start of the intervention; t3: end of the first intervention cycle; t4: end of the 2nd intervention cycle/study end) magnetic resonance imaging was performed and symptoms related to depression were assessed employing the Center for Epidemiological Studies Depression (CES-D) Scale. The intervention resulted in a significant increase in the estimated maximum oxygen uptake (VO2-Max), measured with a standardized walking test.

DATASET DESCRIPTION: This dataset includes demographic data, data of the CES-D Questionnaire, vo2max and T1 weighted MRI data.

研究方案说明：本研究采用被试内设计，设置为期两周的跑步干预前基线期，随后开展两个连续的干预周期。共设置四个评估时间点：t1为研究启动时；t2为基线期结束、干预启动时；t3为首个干预周期结束时；t4为第二个干预周期结束、研究终止时。所有评估节点均开展磁共振成像（magnetic resonance imaging，MRI）检查，并采用流行病学研究中心抑郁量表（Center for Epidemiological Studies Depression Scale，CES-D）评估抑郁相关症状。本次干预可显著提升通过标准化步行测试测得的预估最大摄氧量（estimated maximum oxygen uptake，VO2-Max）。

数据集说明：本数据集包含人口统计学数据、CES-D问卷数据、VO2max数据以及T1加权磁共振成像（T1-weighted MRI）数据。