Sentence production in latent aphasia (Salis & DeDe, 2022)

<b>Purpose: </b>The purpose of this study was to improve our understanding as to which factors determine online, spoken sentence production abilities of adults with latent aphasia in a discourse context.<b>Method: </b>Discourse samples of the story of Cinderella elicited from AphasiaBank were analyzed with speech analysis software. Participants comprised people with latent and anomic aphasia as well as neurotypical controls (10 per group). Durations of pauses (silent and filled) were analyzed according to (a) the location they occurred (between or within sentences), (b) the syntactic complexity of sentences (simple, complex), and (c) sentence length (number of words). Statistical comparisons were conducted using mixed-effect models.<b>Results: </b>The two clinical groups (latent and anomic) differed from controls in the duration of pauses, both between and within sentences. Syntactic complexity did not exert an effect on either of the two clinical groups as compared with controls. As compared with controls, both clinical groups paused more before long in comparison with short sentences.<b>Conclusion: </b>Reduction in processing speed, which affects the ability to simultaneously maintain multiple linguistic and other cognitive demands associated with planning and monitoring of utterances, is a major factor that compromises sentence production in spoken discourse in latent aphasia.<br><b>Supplemental Material S1. </b>Number of utterances, utterance length, and duration of pauses between and within utterances separately for simple and complex utterances. <br>Salis, C., &amp; DeDe, G. (2022). Sentence production in a discourse context in latest aphasia: A real-time study. <i>American Journal of Speech-Language Pathology</i>. Advance online publication. https://doi.org/10.1044/2022_AJSLP-21-00232

<b>目的：</b>本研究旨在深入理解语篇语境中，哪些因素决定了潜在性失语症（latent aphasia）成人的实时口语句子产出能力。<b>方法：</b>采用语音分析软件对从AphasiaBank获取的灰姑娘故事语篇样本进行分析。参与者包括潜在性失语症、命名性失语症（anomic aphasia）患者以及神经典型对照组（每组10人）。研究依据以下维度分析停顿（沉默与填充停顿）时长：（a）停顿位置（句间或句内）；（b）句子句法复杂度（简单句、复杂句）；（c）句子长度（单词数）。采用混合效应模型进行统计比较。<b>结果：</b>潜在性失语症与命名性失语症两个临床组在句间和句内停顿时长上均与对照组存在差异。句法复杂度对两个临床组与对照组的差异无显著影响。与对照组相比，两个临床组在长句前的停顿次数多于短句前。<b>结论：</b>加工速度下降会影响个体同时满足话语规划与监控相关的多重语言及其他认知需求的能力，这是导致潜在性失语症患者口语语篇中句子产出受损的主要因素。<b>补充材料S1：</b>简单句与复杂句分别对应的话语数量、话语长度及句间与句内停顿时长。<br>Salis, C., & DeDe, G. (2022). 潜在性失语症患者语篇语境中的句子产出：一项实时研究. 《美国言语-语言病理学杂志》. 在线优先出版. https://doi.org/10.1044/2022_AJSLP-21-00232