Clinical data in subjects at all 3 time points (T0, T3, and T6) examined.

All 14 subjects are included in the analysis of parameters related to body weight and lipids. Decreases after RYGB were observed for BMI, weight, fat mass, fat free mass, resting energy expenditure and triglycerides. Leptin was also decreased significantly. While HDL-cholesterol decreased from T0 to T3, HDL-Cholesterol levels recovered by T6 and are confirmed by the lack of change in Apo-A1 levels. Total caloric intake decreased after RYGB; however, the relative proportion of lipid, carbohydrate, and protein consumed remained stable. When considering the 12 subjects not treated with insulin, glucose and insulin levels decreased post RYGB. Estimates for HOMA-IR and HOMA%B decreased while HOMA%S increased after surgery. Data presented as mean±standard error. * represents p

本研究纳入全部14名受试者，用于开展与体重及脂质相关参数的分析。受试者的身体质量指数（Body Mass Index, BMI）、体重、脂肪量、去脂体重、静息能量消耗及甘油三酯水平，均在Roux-en-Y胃旁路术（Roux-en-Y Gastric Bypass, RYGB）后出现降低；瘦素（Leptin）水平亦显著下降。高密度脂蛋白胆固醇（High-Density Lipoprotein Cholesterol, HDL-cholesterol）在T0至T3阶段呈下降趋势，但于T6时恢复至基线水平，该结论可通过载脂蛋白A1（Apolipoprotein A1, Apo-A1）水平无显著变化得以验证。术后总热量摄入有所减少，但膳食中脂质、碳水化合物与蛋白质的相对摄入占比保持稳定。针对未接受胰岛素治疗的12名受试者分析结果显示，其血糖与胰岛素水平在RYGB术后均出现下降。稳态模型胰岛素抵抗指数（Homeostatic Model Assessment of Insulin Resistance, HOMA-IR）、稳态模型β细胞功能指数（Homeostatic Model Assessment of Beta-cell Function, HOMA%B）的估算值均有所降低，而稳态模型胰岛素敏感性指数（Homeostatic Model Assessment of Insulin Sensitivity, HOMA%S）则在术后升高。数据以均值±标准误的形式呈现。* 代表p值