Mycobacterium tuberculosis RGTB327 Genome sequencing. Mycobacterium tuberculosis RGTB327

The project aims to study the differences between the local isolates of Mycobacterium tuberculosis with the standard strains at the genome level. Previous studies both from our lab and others have shown the predominance of ancient strains of M. tuberculosis in South India. We are interested to further study the unique region specific genes and polymorphisms.

本项目旨在从基因组层面，对比结核分枝杆菌（Mycobacterium tuberculosis）本地分离株与标准菌株之间的差异。本实验室及其他研究团队的既往研究均表明，古典型结核分枝杆菌菌株在印度南部地区呈优势流行态势。本研究拟进一步针对独特的区域特异性基因与基因多态性展开深入探究。