For Dan Filtered Data SGA Final.csv from Gestational growth trajectories derived from a dynamic fetal–placental scaling law

Fetal trajectories characterizing growth rates in utero have relied primarily on goodness of fit rather than mechanistic properties exhibited in utero. Here, we use a validated fetal–placental allometric scaling law and a first principles differential equations model of placental volume growth to generate biologically meaningful fetal–placental growth curves. The growth curves form the foundation for understanding healthy versus at-risk fetal growth and for identifying the timing of key events in utero.

以往表征子宫内胎儿生长速率的胎儿轨迹研究，多以拟合优度作为核心依据，而非依托子宫内胎儿所展现的生理机制特性。本研究采用经验证的胎儿-胎盘异速标度定律（fetal–placental allometric scaling law），以及针对胎盘体积生长的第一性原理微分方程模型，生成了具备生物学意义的胎儿-胎盘生长曲线。该曲线可为区分健康与高危胎儿生长状态，以及识别子宫内关键事件的发生时间提供重要研究基础。