A role of subdiaphragmatic vagus nerve in depressive-like phenotypes in Chrna7 gene knock-out mice

The aim of present study was to evaluate whether SDV could affect depression-like phenotypes and reduced expression of synaptic proteins in the medial prefrontal cortex (mPFC) of Chrna7 KO mice. Furthermore, we performed 16s rRNA analysis for gut microbiota composition.

本研究旨在探究SDV能否影响Chrna7敲除（Chrna7 KO）小鼠内侧前额叶皮层（medial prefrontal cortex, mPFC）内的抑郁样表型及突触蛋白表达下调情况。此外，本研究针对肠道菌群组成开展了16S rRNA分析。