small RNA sequencing in zebrafish early developmental stages. Danio rerio

During early vertebrate development, various small non-coding RNAs (sRNAs) such as MicroRNAs (miRNAs) and Piwi-interacting RNAs (piRNAs) are dynamically expressed for orchestrating the maternal-to-zygotic transition (MZT). Systematic analysis of expression profiles of zebrafish small RNAome will be greatly helpful for understanding the sRNA regulation during embryonic development.

在脊椎动物早期发育阶段，微RNA（MicroRNAs, miRNAs）、Piwi互作RNA（Piwi-interacting RNAs, piRNAs）等各类小型非编码RNA（small non-coding RNAs, sRNAs）会呈动态表达，以协调母源到合子转换（maternal-to-zygotic transition, MZT）的进程。对斑马鱼小RNA组的表达谱开展系统性分析，将极大助力解析胚胎发育过程中小非编码RNA的调控机制。