Structural modularity of receptor-binding proteins underlies host-range strategy diversification in Klebsiella pneumoniae phages

Data deposit for: Panicker VR, Smug BJ, Klein-Sousa V, Enright MC, Taylor NMI, Drulis-Kawa Z, Mostowy RJ. "Structural modularity of receptor-binding proteins underlies host-range strategy diversification in Klebsiella pneumoniae phages." bioRxiv 2026. https://doi.org/10.64898/2026.05.12.724579 This archive contains all large binary data files required to reproduce the analyses and figures in the paper above. The associated code is available at: https://github.com/VyshakhRP/RBP-div-hostrange Contents: - 01_raw/02_assemblies/ — Raw lysate assemblies for unpublished Klebsiella pneumoniae phages - 01_raw/03_host_genomes/ — Klebsiella pneumoniae host genome sequences (.fasta) - 01_raw/04_phage_genomes/ — Phage genome sequences (.fasta, .gb) - 02_intermediate/09_af3_predictions/ — AlphaFold 3 structure predictions for all receptor-binding proteins (.cif) - 02_intermediate/14_rbps-ecods/ecod.develop288.domains.txt — ECOD domain database (v20230309, develop288) - 02_intermediate/14_rbps-ecods/ecod.develop288.fasta.txt — ECOD domain FASTA (v20230309, develop288) - 05_output/01_genomes/ — Processed phage genome files - 05_output/03_proteins/ — Protein FASTAs and receptor-binding protein structures Usage: Download the archive, extract it, and place each subdirectory into the corresponding location in the cloned GitHub repository. Full instructions are provided in the repository README under Data Availability. Note: The ECOD database files can alternatively be downloaded directly from http://prodata.swmed.edu/ecod/distributions/ (v20230309 / develop288).