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Summary of viral replication kinetics, nuclear localization, nuclear export capacity, and CRM1 binding of the NP-NES3 consensus sequence mutants.

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https://figshare.com/articles/dataset/_Summary_of_viral_replication_kinetics_nuclear_localization_nuclear_export_capacity_and_CRM1_binding_of_the_NP_NES3_consensus_sequence_mutants_/1137369
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a% virus titer ± SD compared with WT at the 46 h of replication kinetic assay from the Fig. 4C. bNo viral rescue by reverse genetics. c% cell count ± SD with nuclear localization of NP from the Fig. 5B. d−, ±, + indicate not occur, partially occur, occur of nuclear export capacity, respectively derived from the Fig. 6. e% intensity of the pull-downed NP band compared with WT from the Fig. 7C.

a. 相对于野生型(Wild Type, WT)的病毒滴度(virus titer)百分比±标准差(SD),为复制动力学实验中培养46小时的检测结果,数据对应图4C。 b. 未通过反向遗传学技术实现病毒拯救。 c. 具有NP蛋白核定位特征的细胞占比±标准差(SD),数据对应图5B。 d. 符号−、±、+分别代表核输出能力未发生、部分发生及完全发生,数据对应图6。 e. 免疫沉淀富集的NP蛋白条带信号强度占野生型(Wild Type, WT)的百分比,数据对应图7C。
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2014-08-13
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