Growth effects of Peg3DelKO allele in neonates.

(a) Male Peg3DelKO/WT were bred with female wild-type littermates to generate Peg3WT/DelKO pups with the paternal transmission of the mutant allele. Pups were genotyped and weighed at 1 day postpartum (dpp), then compared to the average weight of the litter. The number of pups belonging to each percentile weight range was then graphed to visualize the weight distribution of Peg3DelKO pups in comparison to their wild-type littermates. (b) The same series of analyses were also repeated with the pups at the weaning age (21 dpp). Representative littermates from 1 dpp and 21 dpp are shown with corresponding genotypes indicated (c,d).

(a) 将雄性Peg3缺失敲除/野生型（Peg3DelKO/WT）小鼠与雌性野生型（wild-type，WT）同窝仔鼠交配，以获得携带突变等位基因经父系传递的Peg3野生型/缺失敲除（Peg3WT/DelKO）子代幼鼠。于产后1天（day postpartum，简称dpp）对幼鼠进行基因分型与体重测量，并将其与同窝幼鼠的平均体重进行比较。随后统计各体重百分位区间内的幼鼠数量并绘图，以可视化Peg3DelKO幼鼠与其野生型同窝幼鼠的体重分布差异。
(b) 上述系列分析亦于断奶龄（21 dpp）幼鼠中重复开展。(c,d) 展示了产后1天与断奶龄的代表性同窝仔鼠，并标注了对应的基因型。