Geographic and seasonal variation of the for gene reveal signatures of local adaptation in Drosophila melanogaster

In the early 1980s, the observation that Drosophila melanogaster larvae differed in their foraging behavior laid the foundation for the work that would later lead to the discovery of the foraging gene (for) and its associated foraging phenotypes, rover and sitter. Since then, the molecular characterization of the for gene and our understanding of the mechanisms that maintain its phenotypic variants in the laboratory have progressed enormously. However, the significance and dynamics of such variation are yet to be investigated in nature. With the advent of next-generation sequencing, it is now possible to identify loci underlying adaptation of populations in response to environmental variation. Here, I present results of a genotype-environment association analysis that quantifies variation at the for gene among samples of D. melanogaster structured across space and time. These samples consist of published genomes of adult flies collected worldwide, and at least twice per site of collecti..., , , # Geographic and seasonal variation of the for gene reveal signatures of local adaptation in *Drosophila melanogaster*

Author: Dylan Padilla
Date: 2023-12-12

GENERAL INFORMATION

1. Title of Dataset: Data from: Geographic and seasonal variation of the for gene reveal signatures of local adaptation in *Drosophila melanogaster*

2. Author Information
A. Principal Investigator Contact Information
Name: Dylan J. Padilla Perez
Institution: Arizona State University
Address: School of Life Sciences
Email:

DATA & FILE OVERVIEW

1. Description of datasets

The data used in this study represent a subset of a dataset assembled by the Drosophila Genome Nexus project (DGN), the European Drosophila Population Genomics Consortium (DrosEU), and the Real Time Evolution Consortium (DrosRTEC). This dataset is known as the Drosophila Evolution over Space and Time (DEST), and it is coupled with environmental metadata.

File List:
File 1 Name: samps_10Nov2020.xlx (please conve...

20世纪80年代初，关于黑腹果蝇（Drosophila melanogaster）幼虫觅食行为存在差异的观察，为后续发现觅食基因（foraging gene，简称for）及其相关觅食表型rover和sitter的研究奠定了基础。此后，实验室中关于for基因的分子特征解析，以及对维持其表型变异机制的理解均取得了巨大进展。然而，此类变异在自然环境中的意义与动态尚未得到研究。随着下一代测序技术（next-generation sequencing）的出现，如今已能够识别种群响应环境变异而发生适应的潜在基因座。本文展示了一项基因型-环境关联分析（genotype-environment association analysis）的结果，该分析量化了不同时空结构的黑腹果蝇（D. melanogaster）样本中for基因的变异情况。这些样本包括全球范围内收集的成年果蝇已发表基因组数据，且每个采集点至少进行两次采集……

# 黑腹果蝇中for基因的地理与季节变异揭示局部适应特征

作者：Dylan Padilla
日期：2023年12月12日

通用信息

1. 数据集标题：数据来源：黑腹果蝇中for基因的地理与季节变异揭示局部适应特征

2. 作者信息
A. 首席研究员联系方式
姓名：Dylan J. Padilla Perez
机构：亚利桑那州立大学
地址：生命科学学院
电子邮箱：

数据与文件概述

1. 数据集描述

本研究使用的数据是由果蝇基因组连接项目（Drosophila Genome Nexus，简称DGN）、欧洲果蝇种群基因组学联盟（European Drosophila Population Genomics Consortium，简称DrosEU）及实时进化联盟（Real Time Evolution Consortium，简称DrosRTEC）联合构建的数据集的一个子集。该数据集被称为果蝇时空进化数据集（Drosophila Evolution over Space and Time，简称DEST），并附有环境元数据。

文件列表：
文件1名称：samps_10Nov2020.xlx（请转换……）