Inflammatory cell death, PANoptosis, screen identifies central host factors in coronavirus infection and innate immune responses as therapeutic targets

Whole genome CRISPR screening was used as a technique to identify critical genes involved in activating inflammatory cell death, PANoptosis, in response to coronavirus infection.

本研究借助全基因组CRISPR筛选（Whole genome CRISPR screening）技术，旨在鉴定冠状病毒感染过程中参与激活炎性细胞死亡——泛凋亡（PANoptosis）——的关键基因。