Supplementary Material for: Case Series of Eosinophilic Pustular Folliculitis with Exclusive Scalp and Facial Involvement: A Distinct Entity?

Abstract Eosinophilic pustular folliculitis (EPF) is a rare, non-infectious dermatosis characterized by pruritic, recurrent episodes of follicular papulopustules. Three forms of eosinophilic pustular folliculitis have been described: classic EPF (Ofuji disease), immunosuppression- or HIV-associated EPF, and infantile EPF. Histopathologically, eosinophils are frequently observed within and around the follicular epithelium. In our four non-infant patients with negative anti-HIV antibody results, involvement was limited exclusively to the scalp and face. Based on these findings, we suggest that this presentation may represent a distinct clinical subtype of eosinophilic pustular folliculitis characterized by isolated scalp and facial involvement, and we present this case series to highlight this entity.

摘要：嗜酸性脓疱性毛囊炎（Eosinophilic pustular folliculitis, EPF）是一种罕见的非感染性皮肤病，以瘙痒性、复发性毛囊性丘疹脓疱为特征。目前已报道三种亚型的嗜酸性脓疱性毛囊炎：经典型EPF（奥夫吉病，Ofuji disease）、免疫抑制相关或HIV相关EPF，以及婴儿型EPF。组织病理学检查可见毛囊上皮内部及周围常有嗜酸性粒细胞浸润。本文纳入4例非婴儿型患者，其抗HIV抗体检测结果均为阴性，皮损仅局限于头皮与面部。基于上述发现，我们提出该临床表现或许代表了一类以孤立性头皮面部受累为特征的独特临床亚型，并通过本病例系列对这一疾病实体进行阐释。