Adjusted valuesa for systolic and diastolic blood pressure and coefficient of variation for heart rate (CVRR) at school age in relation to prenatal pesticide exposure and PON1 Q192R genotype.

aResults from linear regression models adjusted for gender, age at examination, maternal smoking in pregnancy, and for systolic and diastolic blood pressure also BMI. CVRR was ln-transformed.*p≤0.05,***p≤0.001 compared to unexposed.#p≤0.05,##p≤0.01 compared to PON1 192QQ in the same exposure group.bDue to technical problems with the Heart Rate Monitor, CVRR was only obtained for 98 (14 QQ and 14 QR/RR unexposed, 23 QQ and 19 QR/RR medium exposed, and 16 QQ and 12 QR/RR high exposed) of the 141 children for whom PON1 genotype was determined.

a. 本研究结果来自经性别、检查时年龄、孕期母亲吸烟情况校正的线性回归模型，针对收缩压与舒张压的分析还额外校正了体质量指数（BMI）。心脏血管反射率（CVRR）经自然对数转换。*p≤0.05、***p≤0.001 表示与未暴露组相比具有统计学差异；#p≤0.05、##p≤0.01 表示与同一暴露组内的PON1 192QQ基因型个体相比具有统计学差异。b. 由于心率监测仪（Heart Rate Monitor）出现技术故障，在完成对氧磷酶1（PON1）基因型检测的141名儿童中，仅98名获取到了CVRR数据，具体分组为：未暴露组14名QQ型、14名QR/RR型；中等暴露组23名QQ型、19名QR/RR型；高暴露组16名QQ型、12名QR/RR型。