ZMYND8 transcriptome in trastuzumab resistant breast tumor cells

ZMYND8 regulates genes involved in trastuzumab resistance. Isogenic cells were transduced with lentivirus containing ZMYND8 sgRNAs and subjected to mRNA-seq.

ZMYND8可调控参与曲妥珠单抗（trastuzumab）耐药的基因。将同基因细胞系用携带ZMYND8单向导RNA（single guide RNA，sgRNA）的慢病毒进行转导，并对其开展mRNA测序（mRNA-seq）。