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Usp44 binds centrin to regulate centrosome positioning and suppress tumorigenesis

ChEBI2013-09-01 更新2026-07-21 收录

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40791 数据链接链接失效反馈

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Usp44 binds centrin to regulate centrosome positioning and suppress tumorigenesis

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2013-09-01

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激酶信号通路

Cyclin C was cloned as a growth-promoting G1 cyclin1,2, and several studies postulated a role for cyclin C in driving cell proliferation3-8 . Moreover, cyclin C, together with its kinase partner, th

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SOLUTION NMR STRUCTURE OF TUMOR SUPPRESSOR P16INK4A, RESTRAINED MINIMIZED MEAN STRUCTURE

蛋白质结构解析

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SOLUTION NMR STRUCTURE OF TUMOR SUPPRESSOR P16INK4A, RESTRAINED MINIMIZED MEAN STRUCTURE Descriptor: TUMOR SUPPRESSOR P16INK4A Authors: Byeon, I.-J.L, Li, J, Ericson, K, Selby, T.L, Tevelev, A, Kim, H

Protein Data Bank Japan2024-05-22 更新50

PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis

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铁死亡调控

The tumor suppressor protein p53 suppresses cancer by regulating processes such as apoptosis, cell cycle arrest, senescence, and ferroptosis. Whereas numerous p53 target genes have been identified, o

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A Small Molecule Activator of the TET2 Tumor Suppressor. A Small Molecule Activator of the TET2 Tumor Suppressor

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药物靶点结合

TET2 protein is a dioxygenase that oxidizes 5-methylcytosine and is responsible for DNA demethylation. We found that a small molecule drug (3FM-dC) activates the enzyme activity of TET2. The sequencin

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Human p53 core domain in the absence of DNA

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Human p53 core domain in the absence of DNA Descriptor: P53 TUMOR SUPPRESSOR, ZINC ION Authors: Wang, Y, Rosengarth, A, Luecke, H. Deposit date: 2006-12-20 Release date: 2007-03-06 Last modified: 2023

Protein Data Bank Japan2023-08-30 更新50

Usp44 binds centrin to regulate centrosome positioning and suppress tumorigenesis

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