Coronal Suture, WT, Fgfr2+/S252W (Apert syndrome mouse model), Twist1+/- (Saethre-Chotzen syndrome mouse model), E14.5

RNA-Seq libraries are from laser capture microdissections of C57BL/6J Fgfr2+/+ (W) and C57BL/6J Apert syndrome EIIA-Cre+;Fgfr2+/S252W (A) mice, at development stages TS22/E14.5, from the coronal suture (S), with 5 biological replicates (1-5), of the suture mesenchyme (SM), frontal (FR) osteogenic fronts, and parietal (PA) osteogenic fronts. “W4C1SM”, for example, indicates WT, E14.5, coronal suture, replicate 1, suture mesenchyme.

RNA测序文库来源于C57BL/6J Fgfr2+/+野生型小鼠（简称W）与C57BL/6J Apert综合征EIIA-Cre+;Fgfr2+/S252W模型小鼠（简称A）的激光捕获显微切割样本。样本取自发育阶段为TS22/胚胎14.5天（E14.5）的小鼠冠状缝（S）区域，涵盖缝间充质（SM）、额骨成骨前沿（FR）及顶骨成骨前沿（PA）三种组织类型，每种类型各含5个生物学重复（编号1-5）。例如，样本标识“W4C1SM”代表野生型（WT）、胚胎14.5天、冠状缝、重复1、缝间充质。