SOX2 is required independently in both stem and differentiated cells for pituitary tumor genesis in p27 null mice I

Characterization of the initiation and development of pituitary intermediate lobe tumors in p27-/- mice. Overall design: Transcriptomic analyses from two- and seven-months old dissected pituitary intermediate lobe obtained from wt and p27-/- mice.

p27基因敲除（p27-/-）小鼠垂体中间叶（pituitary intermediate lobe）肿瘤的发生与发展特征分析。实验设计概述：对2月龄与7月龄野生型（wild type, WT）及p27-/-小鼠解剖获取的垂体中间叶组织进行转录组分析。