Erythrolamprus reginae liver, tongue, stomach and intestine transcriptome

This study investigates the molecular responses underlying dietary adaptation and detoxification in the Amazonian Royal Ground snake Erythrolamprus reginae, which preys on chemically defended amphibians such as Ameerega trivittata. We hypothesized that ingestion of toxic prey would not only upregulate digestive enzymes but also activate detoxification mechanisms. To test this, we generated transcriptomes from four key digestive tissues (tongue, stomach, liver, and gut) in E. reginae individuals that had consumed A. trivittata (n = 3), Scinax ruber (n = 3), or were fasting (n = 3). This dataset provides critical insights into the molecular candidates involved in the detoxification cascade following the ingestion of toxic prey, enhancing our understanding of the evolutionary dynamics of predator-prey interactions in Neotropical ecosystems.

本研究针对以具有化学防御机制的两栖动物（如细纹箭毒蛙Ameerega trivittata）为食的亚马逊皇游蛇（Erythrolamprus reginae），探究其饮食适应与解毒过程背后的分子响应机制。我们提出假设：摄入有毒猎物不仅会上调消化酶的表达，还会激活机体的解毒机制。为验证该假设，我们对三组亚马逊皇游蛇个体的四种关键消化组织（舌、胃、肝脏与肠道）进行转录组（transcriptome）测序：三组个体分别为摄入细纹箭毒蛙者（n = 3）、摄入红蹼树蛙Scinax ruber者（n = 3）以及禁食组（n = 3）。本数据集为解析摄入有毒猎物后解毒级联反应相关的分子候选靶点提供了关键依据，有助于加深我们对新热带生态系统中捕食者-猎物相互作用进化动态的理解。