NHLBI TOPMed: Pulmonary Fibrosis Whole Genome Sequencing

This is a set of cases diagnosed with idiopathic pulmonary fibrosis, a fatal interstitial lung disease. These cases were included in the TOPMed phase three studies. The planned study will compare these cases to within-TOPMed controls for genome-wide association studies.

本数据集收录了一批确诊为特发性肺纤维化（idiopathic pulmonary fibrosis）的病例，该病是一种致命性间质性肺病。上述病例已被纳入TOPMed三期研究。本次计划开展的研究将针对全基因组关联研究（genome-wide association studies），将该批病例与TOPMed内部对照样本进行比对分析。