A Photoinduced Cobalt-Catalyzed Synthesis of Pyrroles through in Situ-Generated Acylazirines

Tetrasubstituted pyrroles can be synthesized in a one-pot procedure from isoxazoles. The process includes the photoinduced in situ formation of acylazirines combined with a subsequent cobalt­(II)-catalyzed ring expansion with 1,3-diketones.

四取代吡咯（Tetrasubstituted pyrroles）可通过以异噁唑（isoxazoles）为起始原料的一锅法合成。该反应过程包含光诱导原位生成酰基氮丙啶（acylazirines），以及后续由钴(II)催化的、与1,3-二酮类化合物发生的环扩张反应。