Empirical power for GWAS under no population stratification.

Empirical powers are calculated from 2,000 replicates at the genome-wide significance level 0.05 from Bonferroni method under no population stratification. LIP stands for the proposed method using Liptak method to combine pFBATi and pTi.VAN and ION indicate the VanSteen approach screening top 20 SNPs and Ionita approach using an exponential weighting scheme with partitioning parameters of K = 7 and r = 2 respectively. FBAT are the results only from the within-family component and POP is the standard population-based method.

在无群体分层（population stratification）的条件下，采用邦费罗尼校正法（Bonferroni method），基于2000次重复实验计算全基因组显著性水平为0.05时的经验检验效能。
LIP指本文提出的采用Liptak法整合pFBATi与pTi的方法；VAN与ION分别代表VanSteen方法与Ionita方法：其中VAN方法用于筛选前20个单核苷酸多态性位点（single nucleotide polymorphism, SNPs），ION方法采用指数加权方案，二者的分区参数分别为K=7与r=2。
FBAT为仅采用家系内分量得到的分析结果，POP则为标准的基于群体的分析方法。