Enrichment of H3K9me2 on unsynapsed chromatin in C. elegans does not target de novo sites [ChIP-Seq]. Caenorhabditis elegans

Characterization of the H3K9me2 distribution in the C. elegans adult hermaphrodite genome using ChIP-Seq Overall design: Examination of H3K9me2 in two different nematode strains: fer-1 control and fer-1;him-8 mutant, where the X chromosomes are unsynapsed. The fer-1 mutation prevents production of embryos.

基于染色质免疫共沉淀测序（ChIP-Seq）的秀丽隐杆线虫（C. elegans）成年雌雄同体基因组组蛋白H3第9位赖氨酸二甲基化（H3K9me2）分布特征解析
实验设计：对两种不同线虫品系开展H3K9me2分析：fer-1对照品系与fer-1;him-8突变体品系，该突变体的X染色体无法发生联会。fer-1突变可阻断胚胎的生成。