Study of TCR diversity on human liver transplantation.

T cells are key mediators of alloresponse during liver transplantation (LTx). However, the dynamics of donor-reactive T cell clones in peripheral blood after liver transplantation. In this study, serial PBMC and liver samples were collected from liver recipients for T cell receptors repertoire analyses.

T细胞是肝移植（liver transplantation，缩写LTx）过程中同种异体应答的关键介导因子。然而，肝移植后外周血中供体反应性T细胞克隆的动态变化。本研究从肝移植受者体内采集系列外周血单个核细胞（peripheral blood mononuclear cell，缩写PBMC）及肝脏样本，用于T细胞受体库分析。