Additional file 6 of Buffy coat signatures of breast cancer risk in a prospective cohort study

Additional file 6. Supplementary Table 6. Top GO Biological Processes, GO Cellular Components, GO Molecular Functions, Reactome, and KEGG Pathways enriched from significantly differentially methylated regions (FDR < 0.05, group mean difference > 0.075) identified when overlapping DMRs identified in the main analysis with DMRs identified when samples were limited to participants aged 50 and above at recruitment.

附加文件6，补充表6。本表汇总了从满足筛选标准的显著差异甲基化区域（differentially methylated regions, DMR）中富集得到的排名靠前的基因本体（Gene Ontology, GO）生物学过程、基因本体细胞组分、基因本体分子功能、Reactome通路以及京都基因与基因组百科全书（Kyoto Encyclopedia of Genes and Genomes, KEGG）通路。其中显著差异甲基化区域的筛选条件为错误发现率（false discovery rate, FDR）<0.05且组均值差异>0.075；该区域集为将主分析中鉴定的DMR，与仅纳入招募时年龄≥50岁参与者的样本所鉴定的DMR取交集后得到的区域。