Chemicals enriched in NRF2 active biosets.

NIAID Data Ecosystem2026-03-12 收录

NRF2信号通路

化学物质富集

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https://figshare.com/articles/dataset/Chemicals_enriched_in_NRF2_active_biosets_/13016305 数据链接链接失效反馈

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资源简介：

Chemicals enriched in NRF2 active biosets.

富集于核因子E2相关因子2（Nuclear factor erythroid 2-related factor 2，NRF2）激活型生物数据集（biosets）的化学物质

创建时间：

2020-09-28

Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies. Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

乳腺癌分子机制

NRF2信号通路

Breast–mammary epithelial cells experience different local environments during tissue development and tumorigenesis. Microenvironmental heterogeneity gives rise to distinct cell-regulatory states whos

NIAID Data Ecosystem70

Double vulnerability of active-NRF2 Lung Squamous cell carcinoma to NRF2 and TRIM24

鳞状细胞癌治疗靶点

NRF2信号通路

Lung squamous cell cancer (LUSC) is associated with very poor survival due to the lack of specific treatments. A common genetic alteration in LUSC involves mutations in NFE2L2 (also named NRF2) or its

NIAID Data Ecosystem20

A549 NRF NT, mock and knockout RNAseq

NRF2信号通路

肿瘤免疫逃逸

The NRF2 pathway is frequently activated in various cancer types, yet a comprehensive analysis of its effects across different malignancies is currently lacking. We developed a robust NRF2 activity me

NIAID Data Ecosystem20

NRF2-dependent ECM - Nrf2-Mediated Fibroblast Reprogramming Drives Cellular Senescence by Targeting the Matrisome

细胞衰老机制

NRF2信号通路

Nrf2-mediated fibroblast reprogramming drives cellular senescence by targeting the matrisome. ECM was isolated from WT and NRF2-/- mouse fibroblasts and analyzed by label-free quantification.

NIAID Data Ecosystem40

Additional file 1 of TNFAIP2 confers cisplatin resistance in head and neck squamous cell carcinoma via KEAP1/NRF2 signaling

化疗耐药性

NRF2信号通路

Additional file 1. Figure S1. (a) TNFAIP2 mRNA expression between HNSCC and normal tissues from the TCGA. (b) Kaplan‒Meier survival curve of HNSCC patients with low versus high TNFAIP2 expression from

Figshare2023-08-01 更新20

Chemicals enriched in NRF2 active biosets.

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