Imaging characteristics.

BackgroundCOVID-19 is associated with cardiac dysfunction. This study tested the relative prognostic role of left (LV), right and bi- (BiV) ventricular dysfunction on mortality in a large multicenter cohort of patients during and after acute COVID-19 hospitalization.Methods/ResultsAll hospitalized COVID-19 patients who underwent clinically indicated transthoracic echocardiography within 30 days of admission at four NYC hospitals between March 2020 and January 2021 were studied. Images were re-analyzed by a central core lab blinded to clinical data. Nine hundred patients were studied (28% Hispanic, 16% African-American), and LV, RV and BiV dysfunction were observed in 50%, 38% and 17%, respectively. Within the overall cohort, 194 patients had TTEs prior to COVID-19 diagnosis, among whom LV, RV, BiV dysfunction prevalence increased following acute infection (pConclusionsLV, RV and BiV function declines during acute COVID-19 infection with each contributing to increased in- and out-patient mortality risk. RV dysfunction independently increases mortality risk.

背景：新型冠状病毒肺炎（COVID-19）与心功能障碍相关。本研究旨在评估急性COVID-19住院期间及出院后，左心室（LV）、右心室（RV）及双心室（BiV）功能障碍对患者死亡率的相对预后价值。方法与结果：本研究纳入2020年3月至2021年1月期间，纽约市四家医院中所有在入院30天内接受临床指征经胸超声心动图（TTE）的住院COVID-19患者。由对临床数据设盲的中央核心实验室对超声图像进行重新分析。最终共纳入900例患者（其中28%为西班牙裔，16%为非裔美国人），左心室、右心室及双心室功能障碍的检出率分别为50%、38%及17%。在全部队列中，有194例患者在确诊COVID-19前即接受过TTE检查，其急性感染后左心室、右心室及双心室功能障碍的患病率均有所升高（p结论：急性COVID-19感染期间，左心室、右心室及双心室功能均出现下降，且各类心室功能障碍均会升高患者的住院及门诊死亡风险；其中右心室功能障碍可独立增加死亡风险。