Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 4A5 on the guide strand
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Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 4A5 on the guide strand Descriptor: DNA (5'-D(*AP*GP*T)-3'), DNA (5'-D(*CP*AP*AP*CP*C*AP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(P*TP*GP*AP*GP*AP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*T)-3'), ... Authors: Sheng, G, Gogakos, T, Wang, J, Zhao, H, Serganov, A, Juranek, S, Tuschl, T, Patel, J.D, Wang, Y. Deposit date: 2017-06-01 Release date: 2018-04-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes. Nucleic Acids Res., 45, 2017
嗜热栖热菌(T. thermophilus)Argonaute蛋白(Argonaute)与向导链带有4A5凸起的复合物的晶体结构
描述符:DNA (5'-D(*AP*GP*T)-3')、DNA (5'-D(*CP*AP*AP*CP*C*AP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3')、DNA (5'-D(P*TP*GP*AP*GP*AP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*T)-3')……
作者:Sheng, G、Gogakos, T、Wang, J、Zhao, H、Serganov, A、Juranek, S、Tuschl, T、Patel, J.D、Wang, Y
提交日期:2017-06-01
发布日期:2018-04-18
最后修改日期:2023-11-22
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率3.1埃(Å)
引用:《基于结构与切割机制的嗜热栖热菌Argonaute沉默复合物中凸起位点的螺旋扰动研究》,《核酸研究(Nucleic Acids Res.)》,第45卷,2017年
创建时间:
2017-06-01



