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Conservation of yeast proteins involved in N-linked glycosylation.

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Figshare2015-12-02 更新2026-04-29 收录
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Genes are broadly categorized by function. Human genes are identified by name when possible and the corresponding congenital disorders of glycosylation (CDG, with OMIM ID) are shown. For A. thaliana, C. elegans, D. melanogaster, D. rerio, M. musculus, and P. falciparum, boxes marked with “x” indicate that a peptide from this organism was placed in the same OrthoMCL family with the yeast gene. Not shown: SWP1 is homologous to human ribophorin II [30], and SWP1, OST4, OST5, and OST6 do not lie in ortholog families.

基因可按功能进行大类划分。若条件允许,人类基因将以基因名标注,并附带其对应的糖基化先天性障碍(congenital disorders of glycosylation, CDG,附OMIM编号)信息。对于拟南芥(A. thaliana)、秀丽隐杆线虫(C. elegans)、黑腹果蝇(D. melanogaster)、斑马鱼(D. rerio)、小家鼠(M. musculus)以及恶性疟原虫(P. falciparum),标注有"x"的框格代表该物种的一段肽段与酵母基因同属一个OrthoMCL基因家族。未在本数据集中展示的内容包括:SWP1与人类核糖体结合蛋白II同源[30],且SWP1、OST4、OST5及OST6并不属于任何直向同源基因家族。
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2015-12-02
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