cGN_day10_blood_leukocyte_scRNA-seq

A cGN model was induced in WT B6 mice and blood CD3+ cells and CD3- cells were sorted for scRNA-seq analysis.Details can be found in "Type I interferon drives T cell cytotoxicity by upregulation of interferon regulatory factor 7 in autoimmune kidney diseases in mice" by Wang et al. published in Nature Communications (2025).

在野生型B6小鼠（WT B6 mice）中诱导建立慢性肾小球肾炎模型（cGN model），并分选血液中的CD3+细胞与CD3-细胞以进行单细胞RNA测序分析（scRNA-seq analysis）。详细信息可参见Wang等人于2025年发表在《自然通讯》（Nature Communications）上的论文《I型干扰素（Type I interferon）通过上调干扰素调节因子7（interferon regulatory factor 7）驱动小鼠自身免疫性肾病（autoimmune kidney diseases）中的T细胞细胞毒性（T cell cytotoxicity）》。