Supplemental Tables and Figures for Broadney et al, "Effects of interrupting daily sedentary behavior on children’s glucose metabolism: A 6-day randomized controlled trial"

Online Supplemental Material for manuscript submitted to J. Clin Endocrinol Metab eTable_1: Results from unadjusted mixed model for predicting change in primary outcome (insulin mIU/dL) over time (N=89) eTable_2: Results from unadjusted and covariate-adjusted mixed models for three-way interaction for predicting change in primary outcome of insulin (mIU/dL) over time by experimental condition and weight status (N=89) eTable_3: Results from six separate mixed models predicting change in analyte concentrations over time by experimental condition (N=93) eTable_4: Results from five separate mixed models for three-way interaction for predicting change in secondary outcome analyte concentrations over time by experimental condition and weight status (Healthy weight vs overweight/obese ‘OV/OB’; N=93) eFigure_1: Demonstrative continuous data monitoring of a participant executing each of the conditions SIT (completely sedentary behavior for 3h) and SIT+WALK (sedentary behavior interrupted with 3 min of moderate exertion walking on a treadmill every 30 minutes over 3h) eFigure_2: Oral glucose tolerance test results (free fatty acids, cortisol, triglycerides) by condition

提交至J. Clin Endocrinol Metab的手稿的在线补充材料：附表1（eTable_1）：未校正混合模型结果，用于预测主要结局（胰岛素，单位：mIU/dL）随时间的变化（样本量N=89）；附表2（eTable_2）：未校正与协变量校正混合模型结果，用于分析按实验条件与体重状态划分的、对胰岛素主要结局（mIU/dL）随时间变化的三方交互效应（样本量N=89）；附表3（eTable_3）：六项独立混合模型结果，用于预测按实验条件划分的分析物浓度随时间的变化（样本量N=93）；附表4（eTable_4）：五项独立混合模型结果，用于分析按实验条件与体重状态（健康体重 vs 超重/肥胖‘OV/OB’）划分的次要结局分析物浓度随时间变化的三方交互效应（样本量N=93）；附图1（eFigure_1）：1名参与者完成各实验条件的连续性监测演示数据：静坐行为（SIT，3小时完全静息状态）与静坐+步行（SIT+WALK，每30分钟以跑步机进行3分钟中等强度步行打断3小时静坐行为）；附图2（eFigure_2）：不同实验条件下的口服葡萄糖耐量试验结果（游离脂肪酸、皮质醇、甘油三酯）