Analysis of transriptomic dysregulation upon neonatal and adult downregulation of Taf1 isoforms in rodents

We report the gene expression alterations observed in the striatum of 4 months old mice that received neonatal intracerebroventricular injection with specifically designed AAV1miRNA targeting nTaf1 and cnTaf or the scramble control本研究报道了4月龄小鼠纹状体中观测到的基因表达改变，这些小鼠在新生期接受了靶向nTaf1与cnTaf的特异性设计AAV1 miRNA（1型腺相关病毒microRNA）或乱序对照的脑室内注射。