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Cell of origin in AML: Susceptibility to MN1-induced transformation is regulated by the MEIS1/abdB-like HOX protein complex

ChEBI2011-05-19 更新2026-07-21 收录

白血病机制研究

HOX蛋白功能调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-22923 数据链接链接失效反馈

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资源简介：

Cell of origin in AML: Susceptibility to MN1-induced transformation is regulated by the MEIS1/abdB-like HOX protein complex

应用场景：

创建时间：

2011-05-19

白血病机制研究

肿瘤转录组学

Purpose: Karyotype screening in patients with chronic lymphocytic leukemia (CLL) has identified a rare chromosome translocation, t(X;14)(q28;q32), placing the mature T cell proliferation 1 (MTCP1) gen

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Inducible PAX5 expression in a human B lymphoblastic leukemia cell line

白血病机制研究

转录因子功能分析

Hypomorphic mutations of the transcription factor PAX5 occur in one third of B-progenitor acute lymphoblastic leukemias (B-ALLs). To identify PAX5-regulated genes in B-ALL, here we employ inducible ex

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Systematic screening of chromatin factors identifies divergent roles across haematopoiesis and leukaemia [scRNA-Seq]. Systematic screening of chromatin factors identifies divergent roles across haematopoiesis and leukaemia [scRNA-Seq]

造血表观遗传学

白血病机制研究

Cellular differentiation-trajectories require extensive alterations in chromatin structure and function, elicited by a diverse array of chromatin-factors (CFs). Using haematopoiesis as a model-system,

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Role and function of Sox4 in BCR-ABL1 driven pre-B cells. Mus musculus

白血病机制研究

基因功能分析

In order to investigate the function of Sox4 in ALL, we isolated bone marrow cells from Sox4 fl/fl mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven pre-B cells wer

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Additional file 6 of Insights into the mechanism of Arnebia euchroma on leukemia via network pharmacology approach

药物靶点相互作用

白血病机制研究

Additional file 6. Table S4. Weighted component-important target interactions.

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