ToxRefDB v2.1

Toxicity Reference Database (ToxRefDB) contains in vivo study data from over 5900 guideline or guideline-like studies for over 1100 chemicals. By employing a controlled vocabulary for enhanced data quality, ToxRefDB (v2.1, released August 2022) serves as a resource for study design, quantitative dose response, and endpoint and effect controlled vocabulary linked to the required, recommended, or triggered measurements indicated by corresponding guideline specifications. The database can aid in the validation of in vitro high-throughput screening of chemicals and support retrospective and predictive toxicology applications.

毒性参考数据库（ToxRefDB）汇聚了超过5900项指南或类似指南的研究中的体内实验数据，涉及超过1100种化学物质。该数据库通过采用受控词汇以提升数据质量，在2022年8月发布的2.1版本中，成为研究设计、定量剂量反应以及与指南规范中指出的所需、建议或触发的测量相对应的终点和效应受控词汇的资源。ToxRefDB可助力化学物质体内高 throughput 筛选的验证，并支持回顾性和预测性毒理学应用。