Crystal structure of an intramolecular human telomeric DNA G-quadruplex bound by the naphthalene diimide compound, MM41

Protein Data Bank Japan2023-09-13 更新2026-03-21 收录

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Crystal structure of an intramolecular human telomeric DNA G-quadruplex bound by the naphthalene diimide compound, MM41 Descriptor: 4,9-bis{[3-(4-methylpiperazin-1-yl)propyl]amino}-2,7-bis[3-(morpholin-4-yl)propyl]benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone, POTASSIUM ION, human telomeric DNA sequence Authors: Collie, G.W, Neidle, S. Deposit date: 2011-12-06 Release date: 2013-01-02 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structure-based design and evaluation of naphthalene diimide g-quadruplex ligands as telomere targeting agents in pancreatic cancer cells. J.Med.Chem., 56, 2013

结合萘二酰亚胺类化合物MM41的分子内人类端粒DNA G-四链体（G-quadruplex）晶体结构配体描述符：4,9-双{[3-(4-甲基哌嗪-1-基)丙基]氨基}-2,7-双[3-(吗啉-4-基)丙基]苯并[lmn][3,8]菲咯啉-1,3,6,8(2H,7H)-四酮、钾离子、人类端粒DNA序列作者：Collie, G.W.、Neidle, S. 存档日期：2011-12-06 发布日期：2013-01-02 最后修改日期：2023-09-13 测试方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.95 Å 引用文献：基于结构设计并评估萘二酰亚胺类G-四链体配体作为胰腺癌细胞端粒靶向剂，《J.Med.Chem.》，2013年，第56卷

创建时间：

2011-12-06