Supplementary Table 1. mRNA signature for LXR/RXR activation based on unsupervised differential gene expression analysis of isolated mammary epithelial cells (MECs).

This signature indicates many LXR/RXR target genes are robustly upregulated between functional differentiation in pregnancy (P14, pregnant day 14) and post-secretory activation in established lactation (L4, lactation day 4), suggesting that LXR/RXR dimers are activated.

该特征信号显示，在妊娠功能分化阶段（P14，妊娠第14天）与成熟泌乳期的分泌激活后阶段（L4，泌乳第4天）之间，众多肝X受体/类视黄醇X受体（Liver X Receptor/Retinoid X Receptor, LXR/RXR）靶基因均出现显著上调，提示LXR/RXR异二聚体已被激活。