Neuron Morphology data in .swc format from Patch-seq experiments in human neocortex, Cell ID 737159000

Human neocortical neurons display diverse morphology, physiology and gene expression profiles. We use a method called Patch-seq, where these three data modalities are assayed simultaneously from the same neuron, to understand how the genetic profile of human neocortical neuron types corresponds to their morphological and electrophysiological phenotypes. This collection may contain image stacks (TIFF), reconstruction files in image space (.swc, µm), a transformed file (.swc, µm) oriented so that the y axis extends vertically towards the pia surface, and a marker file (.marker, µm) indicating nodes where dendrites were truncated (10), reconstruction was not continued (20), or surface of tissue was closest to soma (30).

人类新皮层神经元具有多样化的形态、生理特征及基因表达谱。我们采用名为Patch-seq的方法——该方法可从同一神经元中同时测定这三种数据模态——以探究人类新皮层神经元类型的基因谱与其形态学及电生理表型之间的对应关系。本数据集可能包含图像堆栈（TIFF）、图像空间中的重建文件（.swc，µm）、经定向处理的转换文件（.swc，µm，其y轴垂直指向软脑膜表面），以及标记文件（.marker，µm）——该文件标记了树突被截断（10）、重建未继续（20）或组织表面离胞体最近（30）的节点。