MicroRNA-seq data of aortas from chronic kidney disease (CKD) induced vascualr calcification mouse model

MicroRNAs (miRNAs) are short noncoding RNAs that impact protein expression, regulating a variety of physiological processes. To date, a few miRNAs have been implicated in the process of vascular calcification; however, our understanding of the miRNAs involved and their regulatory mechanisms remains incomplete.The analysis showed differences of microRNAs in the aortas after CKD induced vascular calcification. Overall design: Examination of MicroRNA profiles of aortas induced by CKD induced vascualr calcification mouse model.

微小RNA（MicroRNAs, miRNAs）是一类短链非编码RNA，可通过影响蛋白质表达调控多种生理过程。截至目前，已有少量微小RNA被证实与血管钙化过程相关，但我们对所涉及的微小RNA及其调控机制的认知仍不完善。分析结果显示，慢性肾脏病（Chronic Kidney Disease, CKD）诱导血管钙化后，小鼠主动脉内的微小RNA表达存在差异。实验设计：检测慢性肾脏病诱导血管钙化小鼠模型的主动脉微小RNA表达谱。