Table_2_Short-term outcomes of physical activity counseling in in-patients with Major Depressive Disorder: Results from the PACINPAT randomized controlled trial.DOCX

IntroductionA physical activity counseling intervention based on a motivation-volition model was developed and delivered to in-patients with Major Depressive Disorders with the aim of increasing lifestyle physical activity. The aim of this study is to evaluate the short-term outcomes of this intervention.
MethodsA multi-center randomized controlled trial was conducted in four Swiss psychiatric clinics. Adults who were initially insufficiently physically active and were diagnosed with Major Depressive Disorder according to ICD-10 were recruited. The sample consisted of 113 participants in the intervention group (Mage = 42 years, 56% women) and 107 in the control group (Mage = 40 years, 49% women). Motivation and volition determinants of physical activity were assessed with questionnaires. Implicit attitudes were assessed with an Implicit Association Test. Physical activity was self-reported and measured with hip-worn accelerometers over 7 consecutive days starting on the day following the data collection.
ResultsAccording to accelerometer measures, step count decreased on average 1,323 steps less per day (95% CI = −2,215 to −431, p < 0.01) over time in the intervention group compared to the control group. A trend was recognized indicating that moderate-to-vigorous physical activity decreased on average 8.37 min less per day (95% CI = −16.98 to 0.23, p < 0.06) over time in the intervention group compared to the control group. The initial phase of the intervention does not seem to have affected motivational and volitional determinants of and implicit attitudes toward physical activity.
ConclusionPhysical activity counseling may be considered an important factor in the transition from in-patient treatment. Methods to optimize the intervention during this period could be further explored to fulfill the potential of this opportunity.
Clinical trial registrationhttps://www.isrctn.com/ISRCTN10469580, identifier ISRCTN10469580.

**引言**：本研究基于动机-意志模型开发了一项身体活动咨询干预方案，并针对重度抑郁障碍（Major Depressive Disorder）住院患者实施该方案，旨在提升患者日常身体活动水平。本研究旨在评估该干预措施的短期效果。
**方法**：本研究在4家瑞士精神科诊所开展多中心随机对照试验。招募初始身体活动不足且符合国际疾病分类第10版（ICD-10）诊断标准的重度抑郁障碍成年患者作为受试者。最终纳入干预组113名受试者（平均年龄42岁，女性占比56%）及对照组107名受试者（平均年龄40岁，女性占比49%）。研究通过问卷评估身体活动的动机与意志决定因素，采用内隐联想测验（Implicit Association Test）评估内隐态度。身体活动情况通过自我报告结合连续7天的髋部佩戴加速度计进行测量，测量周期始于数据收集次日。
**结果**：加速度计测量结果显示，随时间推移，相较于对照组，干预组受试者的每日步数平均每天少减少1323步（95%置信区间：-2215~-431，p<0.01）。同时存在趋势性差异：相较于对照组，干预组受试者的每日中等至高强度身体活动时间平均每天少减少8.37分钟（95%置信区间：-16.98~0.23，p<0.06）。本干预的初始阶段似乎未对身体活动的动机、意志决定因素及内隐态度产生影响。
**结论**：身体活动咨询可被视为住院治疗过渡阶段的重要干预手段。本研究可进一步探索优化该阶段干预方案的方法，以充分发挥该干预措施的应用潜力。
**临床试验注册**：https://www.isrctn.com/ISRCTN10469580，注册编号ISRCTN10469580。