Japan colorectal tumor prevention study: clinical trial by low-dose aspirin (J-CAPP Study II)

Interventions: Medicate
Primary outcome(s): The primary endpoint is set as the incidence of newly diagnosed colorectal Index Lesion (adenomas >= 10 mm in diameter, adenomas with high-grade dysplasia, or invasive cancer) during 4 years observation excluding the first-year observation.
Study Design: single arm study, open(masking not used), uncontrolled control, single assignment, treatment purpose

干预措施：药物治疗
主要结局指标：本研究的主要终点设定为，排除首年随访后，在4年随访周期内新诊断结直肠指标性病变（直径≥10mm的腺瘤、伴高级别上皮内瘤变的腺瘤或浸润性癌）的发生率。
研究设计：单臂研究、开放标签（未采用盲法）、无对照、单分配方案、治疗性研究目的