MOBHunter_Table1Files_Performance

MOBHunter, a pipeline combining 10 high-performing tools and custom algorithms to detect unique genomic regions, diagnostic markers and genetic boundaries of MGE. MOBHunter integrates these predictions, offers evidence-based classifications, and produces GenBank-compatible outputs for visualization, creating a comprehensive platform for MGE analysis of complete genomes of bacteria and archaeas.The process starts with the pipeline setting the environment in which it will work. The script checks for the availability of .gbk files in the defined path. Then, it will proceed to convert the .gbk files into formats required by the other programs. Converted formats include .faa, .ffn, .fna and .ptt.After the required files are created, the pipeline will run all the incorporated 10 programs. The outputs are then processed in a consensus, and the consensus will conduct the scoring of each hit. If a hit is classified by all the incorporated programs, it will receive a higher score.

MOBHunter是一款整合10款高性能工具与自定义算法的生物信息分析流程，可用于检测可移动遗传元件（MGE，Mobile Genetic Elements）的独特基因组区域、诊断标记与遗传边界。该流程整合各类预测结果，提供基于证据的分类功能，并生成兼容GenBank格式的输出文件以支持可视化操作，从而构建起一套针对细菌与古菌完整基因组的可移动遗传元件综合分析平台。
该分析流程首先会配置运行环境。脚本会先检查指定路径下是否存在.gbk格式文件，随后将.gbk格式文件转换为其他分析程序所需的格式，支持的转换格式包括.faa、.ffn、.fna与.ptt。
待所需文件全部生成后，分析流程将运行全部集成的10款工具。随后对所有输出结果进行一致性整合处理，并通过一致性分析模块对每一条命中结果进行评分。若某条命中结果被所有集成工具共同判定分类，则将获得更高的评分。