Safety of surgery for managing hyperthyroidism in patients with or without preoperative euthyroidism: A systematic review and meta-analysis

Clinicians managing hyperthyroid patients who have not yet achieved euthyroid status often face the clinical dilemma of whether to delay surgery or proceed despite the risks. To address this challenge, this systematic review and meta-analysis evaluates postoperative outcomes in patients who were euthyroid versus those who remained hyperthyroid at the time of surgery, aiming to provide evidence-based insights into the safety and efficacy of surgical intervention in these situations.

针对尚未达到甲状腺功能正常状态（euthyroid）的甲状腺功能亢进症（hyperthyroidism）患者开展诊疗的临床医师，时常面临一项临床两难困境：究竟应当推迟手术，还是不顾相关风险继续实施手术。为解决这一临床挑战，本项系统评价（systematic review）与荟萃分析（meta-analysis）对比评估了手术时处于甲状腺功能正常状态与仍处于甲状腺功能亢进状态的患者的术后结局，旨在为此类情境下外科干预的安全性与有效性提供循证依据。